Oh jeez, it really depends… I play all classes (except Heavy), but I do have favorite loadouts:

Scout: Baby Face Blaster, Milk, Boston Basher

Soldier: Cow Mangler, Buff Banner/Bison, Escape Plan

Pyro: Strange Stock, Scorch Shot, Neon Anihilator

Demo: Loose Cannon, Splendid Screen, Claidhem Mor

Engie: Frontier Justice, Short Circuit, Jag

Medic: Crusader’s Crossbow, Strange Quickfix, Amputator

Sniper: Stock, Cozy Camper, Conscientous Objector

Spy: L'etranger, Spycicle, Stock Watch, Red Tape Trollcorder